Drive efficiency in your biopharmaceutical manufacturing process.
Increasing cell densities and titers in pharmaceutical manufacturing, along with changing regulations and the desire for single-use technologies, are driving developments in the harvest and clarification of cell culture. 3M can help you address these trends in cell culture purification while driving efficiency in your biopharma manufacturing, whether you are using depth filtration or next-generation technologies like fiber chromatographic clarification.
Advancements in cell culture engineering means higher productivity and higher cell densities. This has shifted the burden to clarification and downstream processing. Learn how we can help to efficiently separate cells, cell debris and DNA from the harvest fluid with single-step chromatographic clarification.
Depth filters use porous filtration media to retain particles throughout the media, rather than just on the media surface. They are commonly used when process fluid contains a high particle load because, relative to other types of filters, they can retain a large mass of particles before becoming clogged.
High-performance filter media combined with proper media selection and sizing can provide excellent throughput performance and filtration efficiency for legacy processes. 3M™ Zeta Plus™ EXT Series Depth Filters’ dual-layer construction can enhance the filter’s contaminant holding capacity, reducing premature plugging and helping extend the service life of the media.
Industry leaders discuss next-generation bioprocess and future approaches that deliver high productivity, increased manufacturing flexibility and increased speed with reduced risk.
Cell harvesting and clarifications are both crucial steps that can have a significant impact on the design of downstream processes. By mapping the diferent process inter-dependencies, harvest and clarification operation can be optimized.
From Frost & Sullivan, "A Virtual Think Tank Executive Summary - A Frost & Sullivan Perspective on Next Generation Harvest Techniques" summarizes discussions from academic and industry leaders.
Fill out this form for any technical, business or process-related question, and an appropriate 3M Biopharmaceutical representative will contact you to answer your question or direct your request.
One step can transform your mAb and recombinant protein manufacturing process. At 3M, we’re helping build better, more efficient and simpler manufacturing processes by developing solutions to enhance biologic drug recovery that leads to improved process economics.
Getting the most out of your manufacturing process with speed and on budget is an increasing challenge. Our solutions may help you develop manufacturing processes for vaccines to help maximize purity, leading to overall process economics.
If you need solutions for catalyst removal and recovery, color removal, particulate filtration and fill-finish, 3M offers a wide range of adsorptive depth filters and membrane products for application in chemical pharmaceutical manufacturing.
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