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  • 3M™ Emphaze™ AEX Series Hybrid Purifier
  • 3M™ Emphaze™ AEX Series Hybrid Purifier

    Products
    • Reduces turbidity, HCP, DNA and bioburden
    • Excellent throughput and mAb recovery
    • Enhanced capture column performance and protection
    • Substantial turbidity, DNA, HCP and bioburden reduction.
     More...
    Overall Diameter (Metric)
    Overall_Diameter_Metric
    Overall Length (Metric)
    Overall_Length_Metric
    Overall Width (Metric)
    Overall_Width_Metric
    Overall Height (Metric)
    Overall_Height_Metric
    Micron Rating
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     Overall Diameter (Metric), Overall Length (Metric), Overall Width (Metric), Overall Height (Metric)  Micron Rating
    All Models
    • Overall Diameter (Metric)
      Overall Length (Metric)
      Overall Width (Metric)
      Filter Type
      Overall Height (Metric)
      Micron Rating
    • 3M™ Emphaze™ AEX Series Hybrid Purifier BV0.3R, EMP101AEX020R, 4/Case
      Overall Diameter (Metric)
      2.2 cm
      Overall Length (Metric)
      29.6 cm
      Overall Width (Metric)
      21.5 cm
      Filter Type
      Filter Capsule
      Overall Height (Metric)
      3 cm
    • 3M™ Emphaze™ AEX Series Hybrid Purifier BV5600R, EMP770AEX020R, 1/Case
      Overall Diameter (Metric)
      45.2 cm
      Overall Length (Metric)
      20.3 cm
      Overall Width (Metric)
      45.2 cm
      Micron Rating
      0.2 μm
      Filter Type
      Filter Capsule
      Overall Height (Metric)
      20.3 cm
    • 3M™ Emphaze™ AEX Series Hybrid Purifier, BV8R, EMP301AEX020R, Luer, 2/Case
      Overall Diameter (Metric)
      7.7 cm
      Overall Length (Metric)
      4.5 cm
      Overall Width (Metric)
      7.7 cm
      Micron Rating
      0.2 μm
      Filter Type
      Filter Capsule
      Overall Height (Metric)
      4.5 cm
    • 3M™ Emphaze™ AEX Series Hybrid Purifier BV800R, EMP710AEX020R, 1/Case
      Overall Diameter (Metric)
      45.2 cm
      Overall Length (Metric)
      5.7 cm
      Overall Width (Metric)
      45.2 cm
      Micron Rating
      0.2 μm
      Filter Type
      Filter Capsule
      Overall Height (Metric)
      5.7 cm
    • 3M™ Emphaze™ AEX Series Hybrid Purifier, BV60R, EMP503AEX020R, 1/Case
      Overall Diameter (Metric)
      21.6 cm
      Overall Length (Metric)
      10.1 cm
      Overall Width (Metric)
      24.1 cm
      Filter Type
      Filter Capsule
      Overall Height (Metric)
      10.3 cm
    • 3M™ Emphaze™ AEX Series Hybrid Purifier BV360R, EMP533AEX020R, 1/Case
      Overall Diameter (Metric)
      21.6 cm
      Overall Length (Metric)
      15.2 cm
      Overall Width (Metric)
      21.6 cm
      Micron Rating
      0.2 μm
      Filter Type
      Filter Capsule
      Overall Height (Metric)
      15.2 cm
    • 3M™ Emphaze™ AEX Series Hybrid Purifier BV8R, EMP303AEX020R, Sanitary, 2/Case
      Overall Diameter (Metric)
      7.7 cm
      Overall Length (Metric)
      8.8 cm
      Overall Width (Metric)
      7.7 cm
      Micron Rating
      0.2 μm
      Filter Type
      Filter Capsule
      Overall Height (Metric)
      8.8 cm
    • 3M™ Emphaze™ AEX Series Hybrid Purifier BV1R, EMP201AEX020R, 4/Case
      Overall Diameter (Metric)
      3.7 cm
      Overall Length (Metric)
      48.4 cm
      Overall Width (Metric)
      37 cm
      Filter Type
      Filter Capsule
      Overall Height (Metric)
      4.8 cm
    • 3M™ Emphaze™ AEX Series Hybrid Purifier BV120R, EMP513AEX020R, 1/Case
      Overall Diameter (Metric)
      21.6 cm
      Overall Length (Metric)
      21.6 cm
      Overall Width (Metric)
      10.3 cm
      Micron Rating
      0.2 μm
      Filter Type
      Filter Capsule
      Overall Height (Metric)
      10.3 cm
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    Specifications
    Applications
    Adsorptive Depth Filtration, Bioburden Reduction, Cell Culture Clarification, Chromatography and Column Protection, DNA Removal, Plasma Fractionation
    Brand
    Emphaze™
    Dimensions (metric)
    10.3 cm x 21.6 cm, 15.2 cm x 21.6 cm, 20.3 cm x 45.2 cm, 4.5 cm x 7.7 cm, 5.7 cm x 45.2 cm, 8.8 cm x 7.7 cm
    Filter Material
    All-Synthetic Hybrid
    Filter Type
    Filter Capsule
    Flow Rate (metric)
    0.3 Millilitre per Minute, 1 Millilitre per Minute, 100 Millilitre per Minute, 300 Millilitre per Minute, 4700 Millilitre per Minute, 50 Millilitre per Minute, 680 Millilitre per Minute, 8 Millilitre per Minute
    Industries
    Life Sciences
    Maximum Operating Temperature (Celsius)
    40 Degree Celsius
    Micron Rating
    0.2 μm
    Product Series
    AEX
    Series
    Emphaze™ AEX, Emphaze™ AEX Series
    Storage Temperature
    68
    Units per Case
    1, 2, 4
    Product Details
    • Reduces turbidity, HCP, DNA and bioburden
    • Excellent throughput and mAb recovery
    • Enhanced capture column performance and protection
    • Substantial turbidity, DNA, HCP and bioburden reduction.
    • Reduced surface area requirement of the downstream sterilizing grade membrane.
    • May offer differentiated protection of the protein A column for enhanced contaminant clearance performance.
    • All product components comply with United States Pharmacopeia (USP) Class VI 70°C Biological Reactivity Tests, in vivo.

    3M™ Emphaze AEX Hybrid Purifier is our single-use sterilisable and sanitisable. The all-synthetic purification media that contains a Q-functional anion exchange media and a fine particle and bioburden reduction membrane.

    Remove impurities in biopharmaceutical process streams such as DNA, host cell proteins (HCP) and viruses with our all-synthetic, single use 3M™ Emphaze AEX Hybrid Purifier. The composite purification media is comprised of three primary components: anion exchange nonwoven, microporous membrane, and membrane support. The anion exchange media is composed of four layers of polypropylene nonwoven with a covalently attached quaternary ammonium functional polymer. The bioburden reduction membrane is a highly asymmetric polyamide membrane which has nine zones of decreasing pore size, spanning approximately a 20 X range, and terminating with a 0.2 μm rated qualifying layer. This is followed by a polypropylene nonwoven used as a support layer in the capsule. Capsules There are two primary capsule configurations for the Emphaze AEX Hybrid Purifier, Laboratory and Scale-up capsules: - The Laboratory capsule (BV8) has an 8ml bed volume - The Scale-up capsules are constructed from a lenticular media cell design having bed volumes of 120 mls and 360 mls (BV 120 and BV 360 respectively) - The Production capsules are scaled to meet your manufacturing requirements and utilise manifolds in a holder for ease of use A full support package is available for 3M Emphaze AEX Hybrid Purifiers. This package includes Installation and Operation Guides, a Certificate of Quality and a Regulatory Support File.

    Suggested Applications

    • Use for the clarification of mammalian cell cultures and to optimise downstream processes for monoclonal antibodies (mAbs)
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