3M™ Harvest RC

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Single-stage, single-use chromatographic clarification solution.

Replaces primary, secondary, and guard membrane clarification stages.

Remove cells, cell debris and DNA (<500 ppb) from the harvested cell culture fluid.

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  • Single-stage, single-use chromatographic clarification solution
  • Replaces primary, secondary, and guard membrane clarification stages
  • Remove cells, cell debris and DNA (<500 ppb) from the harvested cell culture fluid
  • High mAb product recovery (90-95%)
  • Predictably scales from laboratory to manufacturing
  • Turbidity of 3M™ Harvest RC clarified cell culture fluid <15 NTU

3M™ Harvest RC is the next generation in harvest and clarification technology for high cell density cultures.

This solution is designed as an efficient option to increase monoclonal antibody (mAb) yields while simplifying the upstream process by replacing the centrifuge and/or depth filtration unit operations.

Suggested applications
  • Clarification for CHO harvest cell culture fluid
  • Single-stage chromatographic clarification



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